DNA Ghost:

This note based blog covers bioinformatics and cancer genomics 

August 19, 2020

  In PREVIOUS ARTICLE, we introduced theoretical basis of MCMC, its components and how it approximates the posterior distribution of interest via sampling in high dimension data. Here let's put MCMC into actual application in genomic research.  

  Next Generation S...

July 30, 2020

  In PREVIOUS ARTICLE, we mentioned that Bayesian approach is being used for somatic variant detection. We will pick up this topic from here and spend two articles on building a site specific error model using MCMC for variant detection. Before walking into actual appl...

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