immune-oncology | dna-ghost

DNA Ghost:

This note based blog covers bioinformatics and cancer genomics

The power of biological replicates in statistical analysis

MCMC II: Applying MCMC in somatic variant calling

MCMC: Monte Carlo sampling and Markov Chain

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Technical consideration with cell type decomposition

Ghost recently did some research on cell type decomposition technique, specifically TIL decomposition in tumor sample. TIMER and CIBERSOR...

A glance into tumor microenvironment

Ghost came across this interesting figure on Cell Science and would like to take this opportunity to talk about tumor microenvironment. A...

Dimension reduction in RNA-Seq based model

Ghost encountered dimension reduction problem while designing a model aiming to describe patient's immuno-oncology (IO) status. The model...

Propose a new way of tumor classification for immuno-oncology

First things first, the proposed classification are immune suppressing and immune escaping. Now let's go back for some specifics. Immuno-...

Developing cancer vaccine: Neoantigen identification and beyond

Immunotherapy has been the hot spot in cancer treatment in recent years. As a key component, neoantigen identification is usually done bi...

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